Different anticoagulants are better for different patients. For patients having problems with their current agent, switching to a new generation may be a better choice. While taking Coumadin, it is important to avoid taking antifungals (such as Ketoconazole) and NSAIDs (such as Ibuprofen), which can put the patient at an increased risk for bleeding.
Other medications and dietary supplements that your doctor may advise you to avoid include:
- Aspirin or Non-steroidal anti-inflammatory (ALEVE, Advil, Motrin, Ibuprofen, etc)
- Herbal products or natural remedies and nutritional supplements
- Products containing vitamin K
Other food and drink items to avoid while on Coumadin include:
- Brussels sprouts
- Mustard greens
- Green tea
- Cranberry juice
In order for your healthcare provider to determine the correct dosage, it is necessary to have regular blood tests. These tests are performed in a laboratory or anticoagulation clinic, usually once a week to once a month, as directed. For this reason, it is important to have regular access to a vehicle or someone who can drive you to an appointment. If you cannot meet this requirement, a different anticoagulant may be better for you.
Additionally, for patients who overdose on Coumadin, a prothrombin complex concentrate in a dosage of 50-100 units is recommended. Commonly referred to as an antidote for Coumadin, this prevents patients from bleeding fatally if too much Coumadin is in their system.